Friday, 14 March 2008
  Joint Symposium with CLINIGENE
8.30 – 10.30 a.m. Gene Therapy:
Perspectives and Clinical Implications
Chair: B. Gansbacher, D. Klatzmann
8.30 – 8.55 a.m.


8.55 – 9.20 a.m.


9.20 – 9.45 a.m.


9.45 – 10.10 a.m.


10.10 – 10.35 a.m.


10.35 – 10.45 a.m.

Gene therapy/immunotherapy of glioblastoma
N. Kasahara, Los Angeles

Manipulating regulatory T cells for cancer therapy
D. Klatzmann, Paris

Oncolytic adenoviruses for treatment of resistant tumours
P. Holm, Munich

Antisense strategies in prostate cancer
I. Eder, Innsbruck

Pdcd4, a colon cancer prognostic regulated by a micro-RNA
H. Allgayer, Mannheim

Free communication
Allogeneic gene-modifi ed tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma – a phase I trial
A. Buchner, Munich

10.45 – 11.30 a.m. Coffee Break
11.30 – 12.55 a.m.
Monoclonal Antibodies
Chair: L. Bergmann, G. Riethmüller
11.30 – 11.55 a.m.


11.55– 12.20 a.m.



12.20 – 12.45 a.m.



12.45 – 12.55 a.m.
Things we have learned about the CTLA4 antibodies
J. Gomez-Navarro, New London

A novel 3rd generation CD20 antibody with increased direct cell death induction and ADCC
Paolo Umaña, Schlieren

CD23 monoclonal antibody, lumiliximab, for patients with
chronic lymphocytic leukemia (CLL)
N. Pathan, San Diego

Free communication
The bispecifi c antibody MT110 targeting EpCAM/CD3 induces
specifi c redirected lysis of pleural carcinoma cells of metastatic breast cancer patients
B. Mayer, Munich
12.55 – 2.00 p.m. Lunch
2.00 – 4.05 p.m.
Monoclonal Antibodies
Chair: M.M. Heiss, C. Peschel
2.00 – 2.25 p.m.


2.25 - 2.50 p.m.


2.50 – 3.15 p.m.


3.15 – 3.40 p.m.



3.40 – 4.05 p.m.

Preclinical and early clinical development of cetuximab
O. Kisker, Darmstadt

Role of cetuximab in head and neck cancer
G. Sprinzl, Innsbruck

Resistance mechanisms against EGF blockers
Y. Yarden, Rehovot

EGFR-Inhibition in relation to RAS-mutational status and
microsatellite instability in colorectal cancer
L. Puig, Paris

Intraperitoneal treatment of malignant ascites using the
three-functional antibody catumaxomab – results of a phase 2/3 study
M.M. Heiss, Munich
4.05 - 4.40 p.m. Coffee Break
4.40 - 5.45 p.m.
Signal Transduction
Chair: M. Scheulen, Y. Takaue
4.40 – 4.55 p.m.


4.55 – 5.20 p.m.


5.20 – 5.45 p.m.


8.00 p.m.
Preclinical and clinical development of histone-deacety laseinhibitors
T. Beckers, Freiburg

Imatinib resistance in GIST
H.-U. Schildhaus, Bonn

Preclinical and clinical dvelopment of HSP-90-Inhibitors
S.Y. Sharp, Surrey, UK

Speakers Dinner

Wednesday | Thursday | Friday | Saturday